DTI-measured white matter abnormalities in adolescents with Conduct Disorder
نویسندگان
چکیده
منابع مشابه
DTI-measured white matter abnormalities in adolescents with Conduct Disorder.
Emerging research suggests that antisocial behavior in youth is linked to abnormal brain white matter microstructure, but the extent of such anatomical connectivity abnormalities remain largely untested because previous Conduct Disorder (CD) studies typically have selectively focused on specific frontotemporal tracts. This study aimed to replicate and extend previous frontotemporal diffusion te...
متن کاملFrontotemporal white-matter microstructural abnormalities in adolescents with conduct disorder: a diffusion tensor imaging study.
BACKGROUND Children with conduct disorder (CD) are at increased risk of developing antisocial personality disorder (ASPD) and psychopathy in adulthood. The biological basis for this is poorly understood. A preliminary diffusion tensor magnetic resonance imaging (DT-MRI) study of psychopathic antisocial adults reported significant differences from controls in the fractional anisotropy (FA) of th...
متن کاملFrontotemporal white-matter microstructural abnormalities in adolescents with condact disorder
1 Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, King’s College London, London, UK 2 NIHR Biomedical Research Centre for Mental Health at South London and Maudsley NHS Foundation Trust and Institute of Psychiatry, King’s College London, UK 3 Natbrainlab, Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, King’s College London, Lond...
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The emergence of new modalities such as Diffusion Tensor Imaging (DTI) is of great interest for the characterization and the temporal study of Multiple Sclerosis (MS). DTI indeed gives information on water diffusion within tissues and could therefore reveal alterations in white matter fibers before being visible in conventional MRI. However, recent studies generally rely on scalar measures deri...
متن کاملA Whole-Brain Investigation of White Matter Microstructure in Adolescents with Conduct Disorder
BACKGROUND The biological basis of severe antisocial behaviour in adolescents is poorly understood. We recently reported that adolescents with conduct disorder (CD) have significantly increased fractional anisotropy (FA) of the uncinate fasciculus (a white matter (WM) tract that connects the amygdala to the frontal lobe) compared to their non-CD peers. However, the extent of WM abnormality in o...
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ژورنال
عنوان ژورنال: Journal of Psychiatric Research
سال: 2014
ISSN: 0022-3956
DOI: 10.1016/j.jpsychires.2013.09.015